We are in constant pursuit of breakthroughs that change patients' lives. We create innovations daily to make the world a healthier place. This was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more innovative, draw and keep the best talent, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and embodies the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the heart of all we do. We live our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.