We are in relentless pursuit of breakthroughs that improve patients' lives. We innovate daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more inventive, attract and retain the best people, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and demonstrates our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and represents the value we work to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We fulfill our purpose by seeking the best science in the world, partnering with others in the healthcare system to increase access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.